Coenzyme Q10 (COQ10) is a lipid soluble molecule produced in the body and found in every cell. It aids mitochondrial energy production and protects it from damaging radicals. Many consider CoQ10 the most valuable cardiovascular nutrient since it’s essential for manufacturing ATP (adenosine triphosphate production), a critical source of fuel for the ever-active heart muscle. This nutrient (it’s not a chemical) is an essential energy source for your body’s cells, and it has a role in protein production. The most prominent sites in the body for naturally produced CoQ10 are the heart, kidneys, liver and pancreas. For those taking statins, CoQ10 is invaluable as statins also inhibit the synthesis of CoQ10 in the blood and may cause loss of energy and muscular deficiencies. In extreme situations, there may be harmful conditions known as myopathies that manifest as a result of statin intake.
41 trained and untrained subjects were administered 200 mg per day of CoQ10 and then evaluated for muscle CoQ10 concentrations and exercise performance. Acute supplementation with CoQ10 resulted in lower serum SOD oxidative stress and higher muscle CoQ10 concentration during and following exercise. In addition, chronic CoQ10 supplementation demonstrated an increase in plasma CoQ10 concentrations and tended to increase time to exhaustion. These findings indicate that those who took CoQ10 had significantly better physical performance, less fatigue and recovered more quickly from exercise than placebo. View research
Administration of statin can cause side effects such as muscle and joint aches as well as worsening the heart’s left ventricular diastolic function. Along with these effects, statins also lower your body’s levels of coenzyme Q10 . A study evaluated left ventricular diastolic function with Doppler echocardiography before and after statin therapy. 10 of the 14 patients (71%) had worsening in greater than 1 marker of Left Ventricular diastolic function (LVDF). On the other hand, 8 out 9 patients that received CoQ10 in conjunction with statin therapy demonstrated improved parameters of diastolic function and had a reversal of greater than 1 marker of LVDF. View research
Coenzyme Q10 is an indispensable part of the mitochondrial efforts to synthesize (ATP) energy. During an 11-week study conducted by researchers from University of Southern California, exogenous administered CoQ10 was found in the heart, liver, skeletal muscles and brain matter . CoQ10’s main function in the mitochondria is to transfer of electrons from NADH-Q oxidoreductase (complex I) and succinate-Q oxidoreductase (complex II) to Q-cytochrome c oxidoreductase (complex III) in the mitochondrial electron transport chain’s ever-active drive to make ATP.
CoQ10 is a lipid soluble antioxidant made in the body and available through foods, in particular meats and fish, but also from peanuts, broccoli and parsley. It is made commercially by a process of biological fermentation. For optimum effects, please take your soft gel with the best meal of the day.