Silymarin is a unique flavonoid complex that is derived from milk thistle (Silybum marianum), a small flowering herb that is related to daisy and ragweed. The herb is commonly found growing abundantly in the Mediterranean region. Silymarin is a combination of silybin, silydianin, and silychrisin, three potent, liver-protective flavonoids. The active compounds are proven liver protectants and the herb has been extensively used in people suffering from liver diseases, including alcoholic liver damage. Apart from liver problems, it has been traditionally used to treat menstrual problems, kidney disorders, varicose veins and gallstones.
Silymarin is a potent anti-inflammatory and antioxidant and improves liver function in people with liver damage. It also aids the liver in detoxification.
Our liver could be considered as the most efficient, elegant, complex and sophisticated chemical laboratory. Among other things, the chief activity of liver is detoxification – neutralizing toxins produced in our body or ingested from our environment. Our current lifestyles, unhealthy dietary choices and environmental pollution puts enormous stress on our liver to detoxify potent toxins that can harm our body. These toxins also overwhelm and harm the liver. It is thus obvious that our liver has mechanisms in place to deal with the world’s chemical insults, but sometimes-additional protection is required when there is chronic erosion of the liver’s health. Silymarin offers a powerful way to protect our liver and help it in its activity of detoxification.
A study was conducted on 170 patients with liver damage due to alcohol. The patients were randomly distributed into two groups. One group received silymarin at a dosage of 140 mg three times daily (total of 420 mg per day) and the other group was given a placebo. The study was continued for two years and results demonstrated that the survivability in the silymarin group was significantly higher as compared to the placebo group. Treatment was found to be effective in patients with alcoholic cirrhosis and no side effects were observed. View research
It is well-known that excess consumption of alcohol (ethanol) is harmful for the liver. It induces different kinds of liver damage like fatty liver, liver cancer (hepatic carcinoma) and cirrhosis, by increasing oxidative stress. Oxidative stress happens when rogue chemical entities called “free radicals” are formed in quantities larger than can be neutralized by the body’s antioxidant system. These free radicals damage cellular structures and cause a variety of health problems. In an experimental study, researchers tried to investigate the effects of silymarin on liver functions in an animal model of excess consumption of alcohol (ethanol). Test rodents were distributed into two groups. Both the groups were administered alcohol, but one group was also fed silymarin. The group that was administered only alcohol showed an increase in the amounts of two enzymes – aspartate aminotransferase (AST) and alanine aminotransferase (ALT) – these are the classic biomarkers for liver function, which are found elevated when the liver is in stress. However, the group that was also fed silymarin along with alcohol did not show an increase in the amounts of the two enzymes. The results indicated that silymarin was able to actually inhibit alcohol-induced liver damage and can also regulate triglyceride levels in the blood. It also decreases inflammation of liver tissues due to alcohol action. View research
Oxidative stress due to high glucose concentrations in the kidneys can lead to a condition called diabetic nephropathy. This condition occurs due to extensive damage to podocytes, specialized cells found in a part of the kidney that plays a vital role in filtration – Bowman’s capsules. A study using a lab model to determine the effect of silymarin found that silymarin was able to inhibit the production of superoxide anions (a type of free radical) and restrict damage due to oxidative stress. This points to the traditional use of milk thistle in kidney problems and reaffirms the nephroprotective effects of silymarin. View research
We source silymarin by extracting it from milk thistle seeds using a standardized and industry-approved process to ensure high quality and concentrated form of the active compound.
Silymarin is present in Liver Lift and Silymarin Life. Liver Lift helps combat liver damage and has potent liver-protectants like silymarin, N-acetyl cysteine and alpha lipoic acid. Silymarin Life contains potent antioxidants derived from silymarin, beetroot and turmeric that support liver detox and defense.