Vitamin B12 is a water-soluble vitamin also known as cobalamin , named after the “cobalt” trace metal found at the center of the molecule. It is one of 8 B vitamins known so far, inlcuding (write in the other B’s here). Vitamin B 12 is actively involved in important activities of the cell, like DNA synthesis, amino acid and fatty acid metabolism. It plays an important role in the functioning of brain and nervous system. Fungi, plants and animals are incapable of producing Vitamin B12 and have to largely rely on external sources for intake. Interestingly, bacteria are capable of synthesizing this vitamin.
Vitamin B12 has multiple functions and is necessary for the overall health of the body. It is mainly important for maintaining healthy nerve cells and in the production of nucleic acids (DNA and RNA). It also affects immune system and mood by synthesizing a compound called S adenosylmethionine (SAM-e, a powerful brain and joint nutrient). It also helps keep blood levels of homocysteine in check, which is associated with heart disease.
In a study conducted in India which examined vitamin B 12 levels in 441 middle-aged men, 81% of the test subjects hadlow vitamin B12 levels and 79% had hyperhomocysteinemia (high levels of homocysteine in the blood). The population included 150 urban middle-class residents as well as mix of lower income residents and rural population. The study also revealed that vegetarians had 4.4 times higher risk of low vitamin B12 concentrations and 3.0 times higher risk of hyperhomocysteinemia compared to those who ate non-vegetarian foods frequently. This study demonstrated that low Vitamin B12 and hyperhomocysteinemia are heavily significant in urban, middle-class residents in India. View research
In a population-based study in Sweden, a random sample of 370 non-demented persons, aged 75 years and older and not treated with B12 and folate, was followed for 3 years to detect incident AD (Alzheimer’s Disease) cases. Two cut-off points were used to define low levels of vitamin B12 (≤150 and ≤250 pmol/L) and folate (≤10 and ≤12 nmol/L), and all analyses were performed using both definitions. AD and other types of dementia were diagnosed by specialists.
This study suggested that vitamin B12 and folate may be involved in the development of AD. A clear association was detected only when both vitamins were taken into account, especially among the cognitively healthy subjects. No interaction was found between the two vitamins. Monitoring serum B12 and folate concentration in the elderly may be relevant for prevention of AD. View research
Sources of vitamin B 12 include animal products like meat and shellfish, dairy products, eggs, beef, pork. However, our current lifestyles (for instance, vegetarian or low-meat consumption diet) do not allow us to consume enough of this vital nutrient. And thus, it is necessary to rely on a high quality nutritional supplement that gives our body the required amount of vitamin B12.
Setu Vitamin B12 is made by biological fermentation and its purity is made to exacting USP/EP grade standards.
Beat It, a multivitamin composition for heart health, contains 1mcg of high quality bioavailable vitamin B12.